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Synthesis, Radical-Scavenging Activity, and Redox Behavior of Planar Catechin Derivatives
https://repo.qst.go.jp/records/68714
https://repo.qst.go.jp/records/68714beff02c3-9a85-4cdb-932a-51c602695a20
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-10-12 | |||||
| タイトル | ||||||
| タイトル | Synthesis, Radical-Scavenging Activity, and Redox Behavior of Planar Catechin Derivatives | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Fukuhara, Kiyoshi
× Fukuhara, Kiyoshi× Nakanishi, Ikuo× Kawashima, Tomonori× Tada, Ayako× Yakumaru, Haruko× Ohkubo, Kei× Kanazawa, Hideko× Urano, Shiro× Okuda, Haruhiro× Miyata, Naoki× Anzai, Kazunori× Ozawa, Toshihiko× Fukuzumi, Shunichi× Ikota, Nobuo× 中西 郁夫× 川島 知憲× 薬丸 晴子× 安西 和紀× 小澤 俊彦× 伊古田 暢夫 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The development of novel antioxidants showing a stronger radical-scavenging activity than natural antioxidants has attracted considerable interest to remove reactive oxygen species, which are known to induce oxidative stress and associated diseases. We herein report the synthesis, radical-scavenging activity, and redox behavior of planar catechin derivatives, in which catechol and chroman moieties in natural (+)-catechin are constrained to be planar. The spectroscopic and kinetic studies have demonstrated that the rate of the scavenging reaction of galvinoxyl radical by the planar catechin is about 5-fold faster than that by (+)-catechin in deaerated acetonitrile. | |||||
| 会議概要(会議名, 開催地, 会期, 主催者等) | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | International Society for Free Radical Research 13th Biennial Congress | |||||
| 発表年月日 | ||||||
| 日付 | 2006-08-19 | |||||
| 日付タイプ | Issued | |||||