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Inter-strain variation of apoptotic index of jejunal crypts between mouse systems after gamma ray whole body irradiation
https://repo.qst.go.jp/records/67500
https://repo.qst.go.jp/records/675009b19e591-c9e0-4cc0-bc53-e6b79ed6fbed
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2003-10-09 | |||||
| タイトル | ||||||
| タイトル | Inter-strain variation of apoptotic index of jejunal crypts between mouse systems after gamma ray whole body irradiation | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kitazawa, Chisa
× Kitazawa, Chisa× Iwakawa, Mayumi× Noda, Syuuhei× Oota, Toshie× Gotou, Miyako× Tanaka, Hiroko× Harada, Yoshinobu× Imai, Takashi× 北沢 知佐× 岩川 眞由美× 野田 秀平× 太田 敏江× 中渡 美也子× 田中 裕子× 原田 良信× 今井 高志 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In the clinic, interindividual differences in normal tissue response to radiotherapy have been observed and genetic factors are suggested to be responsible for this variation. Murine models have proven to be useful for the study of cytotoxic agents including radiation on the jejunum. We here report three murine strain differences in the levels of radiation-induced apoptosis in jejunal crypt cells. The apotosis positivity cell in jejunum carried out apoptosis index comparatively, and radiation susceptibility of strains was evaluated. Apoptosis index in C3 H/Hem was consistently lower than in A/J, or C57BL/6J at various times up to 24 hr after irradiation with 0.5 Gy. (P< 0.05). There was no difference among three strains after irradiation with 5 Gy. In the frequency of appearance of an apoptosis cell, C57BL/6J and A/J were radiation quantity susceptibility as compared with C3 H/Hem. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 日本放射線影響学会第４６回大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2003-10-08 | |||||
| 日付タイプ | Issued | |||||
