@misc{oai:repo.qst.go.jp:00067500, author = {Kitazawa, Chisa and Iwakawa, Mayumi and Noda, Syuuhei and Oota, Toshie and Gotou, Miyako and Tanaka, Hiroko and Harada, Yoshinobu and Imai, Takashi and 北沢 知佐 and 岩川 眞由美 and 野田 秀平 and 太田 敏江 and 中渡 美也子 and 田中 裕子 and 原田 良信 and 今井 高志}, month = {Oct}, note = {In the clinic, interindividual differences in normal tissue response to radiotherapy have been observed and genetic factors are suggested to be responsible for this variation. Murine models have proven to be useful for the study of cytotoxic agents including radiation on the jejunum. We here report three murine strain differences in the levels of radiation-induced apoptosis in jejunal crypt cells. The apotosis positivity cell in jejunum carried out apoptosis index comparatively, and radiation susceptibility of strains was evaluated. Apoptosis index in C3 H/Hem was consistently lower than in A/J, or C57BL/6J at various times up to 24 hr after irradiation with 0.5 Gy. (P< 0.05). There was no difference among three strains after irradiation with 5 Gy. In the frequency of appearance of an apoptosis cell, C57BL/6J and A/J were radiation quantity susceptibility as compared with C3 H/Hem., 日本放射線影響学会第46回大会}, title = {Inter-strain variation of apoptotic index of jejunal crypts between mouse systems after gamma ray whole body irradiation}, year = {2003} }