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頭頸部腫瘍に対する炭素イオン線治療後の口腔‐鼻副鼻腔瘻の危険因子に関する研究
https://repo.qst.go.jp/records/66778
https://repo.qst.go.jp/records/6677881101b86-1290-4330-81e2-fe202c4dce0b
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-04-18 | |||||
| タイトル | ||||||
| タイトル | 頭頸部腫瘍に対する炭素イオン線治療後の口腔‐鼻副鼻腔瘻の危険因子に関する研究 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
小藤, 昌志
× 小藤, 昌志× 高木, 亮× 林, 和彦× 伊川, 裕明× 小藤 昌志× 高木 亮× 林 和彦× 伊川 裕明 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Abstract Purpose: The purpose of this study is to determine the risk factors for developing radiation-induced radiation-induced oroantral or oronasal fistula after carbon-ion radiotherapy. Materials and Methods: Sixty-two patients with oral or sinonasal tumors who were followed up more than 5 years after carbon-ion radiotherapy were included in this study. Carbon-ion radiotherapy was delivered to 57.6 Gy or 64.0 Gy (RBE) /16 fractions. The clinical factors for the radiation-induced oroantral or oronasal fistula were analyzed using multivariate logistic regression model. Results: The median follow up period was 88.8 months. Twenty-three patients (37%) developed the radiation-induced oroantral or oronasal fistula. Multivariate logistic regression analysis showed that the number of the teeth in the volume receiving more than 50 Gy (RBE) was a significant risk factor (odds ratio 2.782). Of the 62 patients, 46 without maxillary invasion were re-analyzed to clarify the effect of the dose-volume factors of the maxilla. The data of maxillary V10-60 and D1-5 were added to the multivariate logistic regression model. Consequently, the number of the teeth in the volume receiving more than 50 Gy (RBE) was a significant risk factor (odds ratio 2.466). Conclusions: The presence of the teeth was the strongest predictive factor for developing oroantral or oronasal fistula. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | H29年度HIMAC共同利用研究成果発表会 | |||||
| 発表年月日 | ||||||
| 日付 | 2018-04-16 | |||||
| 日付タイプ | Issued | |||||
