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Carbon Ion Radiotherapy for Early Breast Cancer

https://repo.qst.go.jp/records/65102
https://repo.qst.go.jp/records/65102
c777fc29-cfca-4e7d-839b-6872111883a8
Item type 会議発表用資料 / Presentation(1)
公開日 2013-08-14
タイトル
タイトル Carbon Ion Radiotherapy for Early Breast Cancer
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Karasawa, Kumiko

× Karasawa, Kumiko

WEKO 641487

Karasawa, Kumiko

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Kamada, Tadashi

× Kamada, Tadashi

WEKO 641488

Kamada, Tadashi

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唐澤 久美子

× 唐澤 久美子

WEKO 641489

en 唐澤 久美子

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鎌田 正

× 鎌田 正

WEKO 641490

en 鎌田 正

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抄録
内容記述タイプ Abstract
内容記述 Introduction :
Breast cancer is a major health problem for women in all over the world. The standard care for early stage breast cancer is breast conserving therapy which consists of conservative surgery and fractionated whole breast irradiation. Fractionated irradiation takes more than 5 weeks and is a burden to patients. Accelerated Partial Breast Irradiation (APBI) is an alternative to fractionated whole breast irradiation in patients with low risk tumor.
Objective :
We are about to conduct a clinical trial of radical APBI without surgery using carbon iron irradiation for patients with low risk tumor. A candidate of carbon ion treatment is T1N0M0, estrogen receptor (ER) positive, HER2 negative, invasive ductal carcinoma or other favorable type, without extensive intraductal component, lymph vascular space invasion, and tumor located more than 5 mm from skin.
Methodology :
Carbon ion beams provide superior physical dose distribution because of their finite range in the target tissue, and they possess a biological advantage due to their high relative biological effectiveness in the Bragg peak. Since 1994, our institute has treated more than 7,000 cases of various malignancies. We plan to use dose escalation of 12 GyE, 13.2 GyE and 15 GyE per fraction and 4 fractions in one week for breast tumor.
Results :
We finalized the technical preparation and ethical approval.
Conclusion :
We will start clinical trial from April 2013. Just a four fractions of carbon ion radiotherapy could have a potential to be an alternative of surgery and conventional radiotherapy.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 29th International Congress of the Medical Women's International Association
発表年月日
日付 2013-08-03
日付タイプ Issued
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