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Induction of Adaptive Response by High LET Heavy Ion Irradiations in Mice
https://repo.qst.go.jp/records/63970
https://repo.qst.go.jp/records/6397007820e35-f84f-444c-b483-e0a3d8d9987f
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2010-08-10 | |||||
| タイトル | ||||||
| タイトル | Induction of Adaptive Response by High LET Heavy Ion Irradiations in Mice | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Bing, Wang
× Bing, Wang× Tanaka, Kaoru× Vares, Guillaume× Shang, Yi× Fujita, Kazuko× Ninomiya, Yasuharu× Nakajima, Tetsuo× Eguchi-Kasai, Kiyomi× Nenoi, Mitsuru× 王 冰× 田中 薫× Ｇｕｉｌｌａｕｍｅ Ｖａｒｅｓ× 尚 奕× 藤田 和子× 二宮 康晴× 中島 徹夫× 笠井 清美× 根井 充 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Characterization of radiation-induced adaptive response provides important scientific information contributing to mechanism research, radiation protection and practical application. In this study, induction of adaptive response by X-rays in combination with high LET irradiations from accelerated heavy ions including carbon, neon, silicon and iron particles was attempted in utero in fetal mice and in vivo in adult mice. In the in utero study, an adaptive response was induced by combination of priming X-irradiations with challenging heavy ion irradiations from carbon or silicon but iron particles; no adaptive response was observable for the combination of priming heavy ion irradiations from carbon, silicon or iron particles with challenging X-irradiations. In the in vivo study, an adaptive response was demonstrated by combination of priming X-irradiations with challenging heavy ion irradiations from carbon or silicon but iron particles; an adaptive response was also observable in the combination of priming heavy ion irradiations from carbon (but neon or silicon) particles with challenging X-irradiations. These findings suggest that induction of adaptive response at whole body level in mice by X-rays in combination with high LET irradiations from accelerated heavy ions is possibly a radiation quality (LET or/and particle) dependent event. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 38th COSPAR Scientifc Assembly | |||||
| 発表年月日 | ||||||
| 日付 | 2010-07-25 | |||||
| 日付タイプ | Issued | |||||
