WEKO3
アイテム
ラット精子形成細胞における粒子線の影響に関する研究(?)
https://repo.qst.go.jp/records/62526
https://repo.qst.go.jp/records/625266febc88f-9950-465c-9126-7e7aff8ec53c
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-04-18 | |||||
| タイトル | ||||||
| タイトル | ラット精子形成細胞における粒子線の影響に関する研究(?) | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
王, 冰
× 王, 冰× 村上, 正弘× 笠井, 清美× 野島, 久美恵× 田中, 薫× 尚, 奕× 藤田, 和子× Ｈｅｒｖｅ, Ｃｏｆｆｉｇｎｙ× 早田, 勇× 王 冰× 村上 正弘× 笠井 清美× 野島 久美恵× 田中 薫× 尚 奕× 藤田 和子× 早田 勇 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Effects of prenatal irradiations on the postnatal developmental alterations were studied following exposure of pregnant Wistar rats to either accelerated carbon-ion beans with a linear energy transfer (LET) value of about 13 keV/micro m or neon-ion beams with a LET value of about 30 keV/micro m at a dose range from 0.1 Gy to 2.0 Gy on gestation day 15. To estimate the RBE values of heavy ion irradiations, the effects of X-rays at 200 kVp estimated for the same biological end points were studied as a reference for comparison. To study the possible difference in the alterations of gene expressions induced by different type of irradiations, the cultured fetal gonads were irradiated and the extracted mRNA was analyzed using HiCEP. Results indicated that prenatal irradiations on gestation day 15 generally induced markedly detrimental effect on fetal development, postnatal testicular maturation and male reproductivity in rats, which was a dose and LET-related event. Investigations using HiCEP on radiation-induced gene expressions in fetal gonad tissues are in progress. |
|||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 平成18年度放射線医学総合研究所重粒子線がん治療装置等共同利用研究発表会 | |||||
| 発表年月日 | ||||||
| 日付 | 2007-04-10 | |||||
| 日付タイプ | Issued | |||||
