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Carbon Ion Radiotherapy for Skull Base and Paracervical Tumors

https://repo.qst.go.jp/records/62487
https://repo.qst.go.jp/records/62487
0b41727c-b878-4290-b25c-a68d1d122dad
Item type 会議発表用資料 / Presentation(1)
公開日 2008-03-26
タイトル
タイトル Carbon Ion Radiotherapy for Skull Base and Paracervical Tumors
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_c94f
資源タイプ conference object
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Hasegawa, Azusa

× Hasegawa, Azusa

WEKO 617359

Hasegawa, Azusa

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Mizoe, Junetsu

× Mizoe, Junetsu

WEKO 617360

Mizoe, Junetsu

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Takagi, Ryo

× Takagi, Ryo

WEKO 617361

Takagi, Ryo

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Bessho, Hiroki

× Bessho, Hiroki

WEKO 617362

Bessho, Hiroki

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Onda, Takeshi

× Onda, Takeshi

WEKO 617363

Onda, Takeshi

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Tsujii, Hirohiko

× Tsujii, Hirohiko

WEKO 617364

Tsujii, Hirohiko

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長谷川 安都佐

× 長谷川 安都佐

WEKO 617365

en 長谷川 安都佐

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溝江 純悦

× 溝江 純悦

WEKO 617366

en 溝江 純悦

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高木 亮

× 高木 亮

WEKO 617367

en 高木 亮

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別所 央城

× 別所 央城

WEKO 617368

en 別所 央城

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恩田 健志

× 恩田 健志

WEKO 617369

en 恩田 健志

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辻井 博彦

× 辻井 博彦

WEKO 617370

en 辻井 博彦

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抄録
内容記述タイプ Abstract
内容記述 Purpose: To estimate the toxicity and efficacy of carbon ion radiotherapy for skull base and paracervical tumors.
Materials and Methods: Between April 1997 and August 2007, a total of 46 patients with skull base or paracervical tumors have been treated with carbon ion radiotherapy for the phase I/II or phase II clinical trials. The 46 patients consisting of 20 males and 26 females, their age range was from 16 to 78, with a median age of 50 years. Histologically, 46 patients had 29 chordoma, 6 malignant meningioma, 7 chondrosarcoma, 3 olfactory neuroblastoma and one giant cell sarcoma.
Results: Median follow-up time in 46 patients was 50 months (range, 4-122 months). At the time of analysis, there was no evidence of any serious acute or late reactions. The five-year local control rates according to prescribed tumor dose were 75% at 48 GyE (n=4), 67% at 52.8 GyE (n=6), 78% at 57.6 GyE (n=9) and 93% at 60.8 GE (n=27), respectively. The five-year overall survival rates were 50% at 48 GyE, 100% at 52.8 GyE, 100% at 57.6 GyE and 76% at 60.8 GyE, respectively. In 29 chordoma patients, they were divided into two groups; a low-dose group (n=10) irradiated with doses ranging from 48 to 57.8 GyE and a high-dose group (n=19) irradiated with a 60.8 GyE. The five-year local control rates were 60% for the low-dose group and 91% for the high-dose group. The five-year overall survival rates were 89% for the low-dose group and 94% for the high-dose group.
Conclusions: Carbon ion radiotherapy will deliver a high local control rates with low toxicity to the surrounding normal tissues.
会議概要(会議名, 開催地, 会期, 主催者等)
内容記述タイプ Other
内容記述 NIRS-MD Anderson Symposium on Clinical lssues for Particle Therapy
発表年月日
日付 2008-03-22
日付タイプ Issued
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