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Dose Distribution of Heavy-ion Scanning Irradiationfor Simulated for Moving Target
https://repo.qst.go.jp/records/61338
https://repo.qst.go.jp/records/61338c653be65-5592-4d03-adf3-e4fb0190f6f4
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2006-05-04 | |||||
| タイトル | ||||||
| タイトル | Dose Distribution of Heavy-ion Scanning Irradiationfor Simulated for Moving Target | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Urakabe, Eriko
× Urakabe, Eriko× Minohara, Shinichi× 新谷 恵理子× 蓑原 伸一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Objective: Heavy ion radiotherapy is characterized its excellent physical dose localization and the biological effectiveness because of its high linear energy transfer (LET). The scanning irradiation of heavy ion, which is the highly conformal techniques, is more sensitive to motion effects. The consequence can be under-dosage of the target volume or over-dosage of critical structures. The effectiveness of scanning irradiation with the respiratory-gated techniques for the moving target is evaluated in this study. Material and Methods: The scanning irradiation using carbon ions is planed to the target contours on a set of 3D CT images. They are converted to the water equivalent depth coordinate and the prescribed dose is set in and around the target region. The Bragg peaks of beams are arranged in the water equivalent space, and the weight of each beam spot is optimized to meet the condition of the prescribed dose. From the optimized beam arrangement and the weight, the planned dose distribution is calculated and displayed on the axial, sagittal, or coronal multiplanar reconstruction CT image. The motion models are constructed based on a set of sequential 3D CT volume (4D CT) data of various clinical cases, such as lung and liver tumor. And the dose distribution simulated for the moving target is evaluated with this model. Results: The scanning-irradiated dose distribution is simulated for the clinical targets based on the motion analysis of tumor. The motion of tumor is analyzed by the direction, distance, speed and variation of density. Especially for the heavy-ion radiotherapy, the density through beam path is crucial because it affects strongly on the dose coverage around the distal end of the tumor. For some clinical moving models, the dose uniformities in planning target volume and the outer dosage on normal tissue are estimated with the timing for respiration. The quantitative analysis with the scanning parameters such as beam size, arrangement and scanning speed, is on going. Conclusion: This simulation of scanning irradiation enables the clinical evaluation of the dose distribution for the moving target. The effect on dose uniformity is estimated and the engineering requirements for the scanning devices can be examined to the tumor on moving target. |
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| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Third International Conference on Translational Research and Pre-Clinical Stratgies in Radiation Oncology | |||||
| 発表年月日 | ||||||
| 日付 | 2006-03-15 | |||||
| 日付タイプ | Issued | |||||
