{"created":"2023-05-15T14:44:52.574246+00:00","id":61338,"links":{},"metadata":{"_buckets":{"deposit":"f2877d53-4fec-4c1d-a981-1c507d77f9bb"},"_deposit":{"created_by":1,"id":"61338","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"61338"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00061338","sets":["10:29"]},"author_link":["607014","607015","607013","607012"],"item_10005_date_7":{"attribute_name":"発表年月日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2006-03-15","subitem_date_issued_type":"Issued"}]},"item_10005_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective:\nHeavy ion radiotherapy is characterized its excellent physical dose localization and the biological \neffectiveness because of its high linear energy transfer (LET). The scanning irradiation of heavy \nion, which is the highly conformal techniques, is more sensitive to motion effects. The \nconsequence can be under-dosage of the target volume or over-dosage of critical structures. The \neffectiveness of scanning irradiation with the respiratory-gated techniques for the moving target is \nevaluated in this study.\nMaterial and Methods:\nThe scanning irradiation using carbon ions is planed to the target contours on a set of 3D CT \nimages. They are converted to the water equivalent depth coordinate and the prescribed dose is set \nin and around the target region. The Bragg peaks of beams are arranged in the water equivalent \nspace, and the weight of each beam spot is optimized to meet the condition of the prescribed dose. \nFrom the optimized beam arrangement and the weight, the planned dose distribution is calculated \nand displayed on the axial, sagittal, or coronal multiplanar reconstruction CT image. The motion \nmodels are constructed based on a set of sequential 3D CT volume (4D CT) data of various \nclinical cases, such as lung and liver tumor. And the dose distribution simulated for the moving \ntarget is evaluated with this model. \nResults:\nThe scanning-irradiated dose distribution is simulated for the clinical targets based on the motion \nanalysis of tumor. The motion of tumor is analyzed by the direction, distance, speed and variation \nof density. Especially for the heavy-ion radiotherapy, the density through beam path is crucial \nbecause it affects strongly on the dose coverage around the distal end of the tumor. For some \nclinical moving models, the dose uniformities in planning target volume and the outer dosage on \nnormal tissue are estimated with the timing for respiration. The quantitative analysis with the \nscanning parameters such as beam size, arrangement and scanning speed, is on going.\nConclusion:\nThis simulation of scanning irradiation enables the clinical evaluation of the dose distribution for \nthe moving target. The effect on dose uniformity is estimated and the engineering requirements for \nthe scanning devices can be examined to the tumor on moving target.","subitem_description_type":"Abstract"}]},"item_10005_description_6":{"attribute_name":"会議概要（会議名, 開催地, 会期, 主催者等）","attribute_value_mlt":[{"subitem_description":"Third International Conference on Translational Research and Pre-Clinical Stratgies in Radiation Oncology","subitem_description_type":"Other"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Urakabe, Eriko"}],"nameIdentifiers":[{"nameIdentifier":"607012","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Minohara, Shinichi"}],"nameIdentifiers":[{"nameIdentifier":"607013","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"新谷 恵理子","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"607014","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"蓑原 伸一","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"607015","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference object","resourceuri":"http://purl.org/coar/resource_type/c_c94f"}]},"item_title":"Dose Distribution of Heavy-ion Scanning Irradiationfor Simulated for Moving Target","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Dose Distribution of Heavy-ion Scanning Irradiationfor Simulated for Moving Target"}]},"item_type_id":"10005","owner":"1","path":["29"],"pubdate":{"attribute_name":"公開日","attribute_value":"2006-05-04"},"publish_date":"2006-05-04","publish_status":"0","recid":"61338","relation_version_is_last":true,"title":["Dose Distribution of Heavy-ion Scanning Irradiationfor Simulated for Moving Target"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-15T21:43:33.360804+00:00"}