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DRINKING BEER REDUCES THE RADIATION INDUCED CHROMOSOME ABERRATIONS IN HUMAN LYMPHOCYTES
https://repo.qst.go.jp/records/60076
https://repo.qst.go.jp/records/60076483caec3-b32d-45bc-a38a-1c26b918d88b
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2003-11-07 | |||||
| タイトル | ||||||
| タイトル | DRINKING BEER REDUCES THE RADIATION INDUCED CHROMOSOME ABERRATIONS IN HUMAN LYMPHOCYTES | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Monobe, Manami
× Monobe, Manami× Ando, Koichi× 物部 真奈美× 安藤 興一 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Search for chemical agents able to protect human beings from radiation damages is a key issue in radiation biology. In fact, radiation protectors are needed for both acute exposures (e.g. nuclear accidents, radiation therapy, or military applications) and low-dose irradiation (diagnostic radiology, high-altitude and space flights, radon indoors, etc.) It has been known that a number of alcohols, which readily react with the hydroxyl radical, are efficient radioprotectors. We here investigated the radioprotective effects of beer intake on human blood. Whole blood was irradiated with 200 kVp X rays and LET 50 keV/um carbons from the HIMAC (the synchrotron) at the National Institute of Radiological Sciences (NIRS, Chiba, Japan). Cultures were initiated using 1.0 ml of irradiated whole blood in 9 ml of RPMI 1640 medium supplemented with 20 % (v/v) fetal bovine serum, 0.06 mg/ml kanamycin, 1.25 mg/ml sodium bicarbonate, 10 ul/ml PHA-M, 0.05 ug/ml colcemid. The irradiated blood cells were plated in T-25 flasks and incubated for 52 hr at 37 C-degree in a humidified atmosphere containing 95 % air plus 5 % CO2. In the present study, we found that radiation induced chromosome aberrations were decreased by intake of beer. The radioprotection was more effective for carbon ions, high-density ionizing radiation, than X rays. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | The 2nd International Workshop on Space Radiation Research | |||||
| 発表年月日 | ||||||
| 日付 | 2002-03-15 | |||||
| 日付タイプ | Issued | |||||
