@misc{oai:repo.qst.go.jp:00060076, author = {Monobe, Manami and Ando, Koichi and 物部 真奈美 and 安藤 興一}, month = {Mar}, note = {Search for chemical agents able to protect human beings from radiation damages is a key issue in radiation biology. In fact, radiation protectors are needed for both acute exposures (e.g. nuclear accidents, radiation therapy, or military applications) and low-dose irradiation (diagnostic radiology, high-altitude and space flights, radon indoors, etc.) It has been known that a number of alcohols, which readily react with the hydroxyl radical, are efficient radioprotectors. We here investigated the radioprotective effects of beer intake on human blood. Whole blood was irradiated with 200 kVp X rays and LET 50 keV/um carbons from the HIMAC (the synchrotron) at the National Institute of Radiological Sciences (NIRS, Chiba, Japan). Cultures were initiated using 1.0 ml of irradiated whole blood in 9 ml of RPMI 1640 medium supplemented with 20 % (v/v) fetal bovine serum, 0.06 mg/ml kanamycin, 1.25 mg/ml sodium bicarbonate, 10 ul/ml PHA-M, 0.05 ug/ml colcemid. The irradiated blood cells were plated in T-25 flasks and incubated for 52 hr at 37 C-degree in a humidified atmosphere containing 95 % air plus 5 % CO2. In the present study, we found that radiation induced chromosome aberrations were decreased by intake of beer. The radioprotection was more effective for carbon ions, high-density ionizing radiation, than X rays., The 2nd International Workshop on Space Radiation Research}, title = {DRINKING BEER REDUCES THE RADIATION INDUCED CHROMOSOME ABERRATIONS IN HUMAN LYMPHOCYTES}, year = {2002} }