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アンチモンによる放射線誘発DNA-dsbの修復阻害
https://repo.qst.go.jp/records/59027
https://repo.qst.go.jp/records/59027a494c175-e093-4ffc-b642-db49ebde666f
| Item type | 会議発表用資料 / Presentation(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2002-05-30 | |||||
| タイトル | ||||||
| タイトル | アンチモンによる放射線誘発DNA-dsbの修復阻害 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_c94f | |||||
| 資源タイプ | conference object | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
佐藤, 宏
× 佐藤, 宏× 高橋, 千太郎× 岡安, 隆一× 久保田, 善久× 孫, 学智× 佐藤 宏× 高橋 千太郎× 岡安 隆一× 久保田 善久× 孫 学智 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Antimony compounds are widely used in various manufacturing and semi-conducting industries, but the biological effect was not well known. Effect of antimony on the repair of radiation induced DNA double strand breaks (DNA-dsb) was studied in Chinese hamster ovary (CHO) cells. CHO cells were treated with antimony trichloride (SbCl3) or antimony potassium tartrate (APT) for 2h. Then DNA-dsb was induced by gamma-irradiation at a dose of 40Gy and the degree of DNA-dsb was determined by gel electrophoresis immediately after irradiation or following 30-min repair period. DNA-dsb repair was completely inhibited by exposure to 0.4mM SbCl3 and the ability of proliferation was sustained at the same concentration. The ability of proliferation was low by exposure to 0.2mM APT, but DNA-dsb repair was not inhibited. | |||||
| 会議概要（会議名, 開催地, 会期, 主催者等） | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | 日本放射線影響学会第44回大会 | |||||
| 発表年月日 | ||||||
| 日付 | 2001-10-31 | |||||
| 日付タイプ | Issued | |||||
