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正常組織障害における放射線感受性遺伝子研究−遺伝子多型からのアプローチー
https://repo.qst.go.jp/records/56850
https://repo.qst.go.jp/records/56850a746e1d7-540f-4607-8105-282dca1352be
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-07-05 | |||||
| タイトル | ||||||
| タイトル | 正常組織障害における放射線感受性遺伝子研究−遺伝子多型からのアプローチー | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
今井, 高志
× 今井, 高志× 岩川, 眞由美× 原田, 良信× 道川, 祐市× 三枝, 公美子× 伴, 貞幸× 相良, 雅史× 辻, 厚至× 野田, 秀平× 今井 高志× 岩川 眞由美× 原田 良信× 道川 祐市× 三枝 公美子× 伴 貞幸× 相良 雅史× 辻 厚至× 野田 秀平 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Cancer patients vary considerably in normal tissue reactions after radiotherapy. It has been hypothesized that the clinical radiosensitivity of normal tissues should be regarded as a so-called complex trait dependent on the cumulative effect of many minor genetic determinants. To identify markers for these determinants, single nucleotide polymorphism (SNP) markers were typed for the candidate genes which were determined by mainly our gene expression analyses. We have investigated genotypes of more than three hundreds individuals consisting of breast cancer, ovarian cancer and prostate cancer patients. Statistical analysis indicated that the SNP types on, at least 12 genes were associated with the radiation-induced adverse effects. | |||||
| 書誌情報 |
癌の臨床 巻 51, 号 5, p. 319-322, 発行日 2005-05 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0021-4949 | |||||
