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Analysis of radiation-induced bystander response between human normal cells and cancer cells
https://repo.qst.go.jp/records/56139
https://repo.qst.go.jp/records/56139000630dd-5c3a-419e-8ed3-ca49eb5e72b9
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2019-03-01 | |||||
| タイトル | ||||||
| タイトル | Analysis of radiation-induced bystander response between human normal cells and cancer cells | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
小林, 亜利紗
× 小林, 亜利紗× 及川, 将一× 古澤, 佳也× Wang, Jun× アッサワプロンポーン, ナロンチャイ× テングゥ, アーマッド テングゥ アブリザル ファリザル× 小西, 輝昭× 小林 亜利紗× 及川 将一× 古澤 佳也× アッサワプロンポーン ナロンチャイ× テングゥ アーマッド テングゥ アブリザル ファリザル× 小西 輝昭 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The aim of radiation cancer therapy as an effective tool is to target the tumor accurately, while limiting the exposure to normal tissue. Although the target is the tumor cells, the exposure effect also occurs in the normal tissue surrounding the tumor area. Therefore, it is essential to investigate the intercellular signaling process between irradiated cells and non-irradiated cells in surrounding areas, known as radiation-induced bystander effect. In previous study, we reported that a signal from the bystander normal cells have modulated the DNA double strand breaks (DSB) repair in irradiated cancer cells exhibiting a rescue effect [1]. However, the question arises now is how radiation-induced bystander effect is facilitated? There are two major pathways that permit cell to cell interaction; Gap-junction and Media Transfer technique. Therefore, in this study we proceed with our previous findings to determine which pathway is involved in rescue effect. | |||||
| 書誌情報 |
平成29年度共用施設（PASTA&SPICE, NASBEE, X/γ線照射装置）成果報告書 p. 25-27, 発行日 2018-12 |
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| 出版者 | ||||||
| 出版者 | 国立研究開発法人量子科学技術研究開発機構 | |||||
