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Protective effects of yeast beta-glucan against the biological damage induced by heavy ion radiation and its related mechanism (16J320)
https://repo.qst.go.jp/records/56068
https://repo.qst.go.jp/records/56068d0c1eb8c-912b-46cd-9ab1-50bc475afb07
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-11-15 | |||||
| タイトル | ||||||
| タイトル | Protective effects of yeast beta-glucan against the biological damage induced by heavy ion radiation and its related mechanism (16J320) | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Lu, Dong
× Lu, Dong× Furusawa, Yoshiya× Konishi, Teruaki× Kobayashi, Alisa× Zhang, Miaomiao× 古澤 佳也× 小西 輝昭× 小林 亜利紗 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | How to effectively reduce the effect of radiation to human is a very important issue. Based on the heavy ion beam, this project is to study the protective effects of yeast â-glucan against heavy ion radiations on the cultured mammalian cells; further to explore the relationship between this protective effect and mammalian cells proliferation related signal pathway. Human lung normal epithelial cell line Beas-2b cells were exposed to Fe ion beams. After irradiation, survive rate, growth curve, apoptosis, and immunofluorescent of the cell samples, with or without pretreat with â-glucan, were analyzed. The results showed there were some protect effect of â-glucan to irradiated mammalian cells. More experiment should be performed to prove those results. We expect the results of this project could provide valuable experimental data for the development of a safe, effective radiation protection health food. | |||||
| 書誌情報 |
平成28 年度放射線医学総合研究所 重粒子線がん治療装置等 共同利用研究報告書 巻 2016, 号 HIMAC-145, p. 96-97, 発行日 2017-09 |
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