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Functional Analysis of pprA and pprI Genes That Are Involved in Radiation/Desiccation Response in the Radioresistant Bacterium Deinococcus grandis
https://repo.qst.go.jp/records/56020
https://repo.qst.go.jp/records/560206aa7f852-67db-4c24-90a1-32e11fc3fa18
Item type | 一般雑誌記事 / Article(1) | |||||
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公開日 | 2017-03-29 | |||||
タイトル | ||||||
タイトル | Functional Analysis of pprA and pprI Genes That Are Involved in Radiation/Desiccation Response in the Radioresistant Bacterium Deinococcus grandis | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kurosawa, Kakeru
× Kurosawa, Kakeru× Omoso, Kota× Takeshita, Hajime× 佐藤, 勝也× 大野, 豊× Narumi, Issay× 佐藤 勝也× 大野 豊 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The genome analysis revealed that Deinococcus grandis possessed RDR regulon as shown in D. radiodurans. In this study, to delineate the function of PprA and PprI in radiation-induced DNA repair, we generated pprA and pprI deletion strains of D. grandis and investigated survivals of the deletion strains and wild type strains following exposure to gamma-rays. The D. grandis pprA deletion strain showed much higher sensitivity to gamma rays compared to the D. radiodurans pprA disruptant strain. On the other hand, the sensitivity of the D. grandis pprI deletion strain was comparable to that of D. radiodurans pprI deletion strain. The fact that the loss of pprA severely affected cell survival highlighted the functional importance of PprA protein in D. grandis. | |||||
書誌情報 |
QST Takasaki Annual Report 2015 p. 137-137, 発行日 2017-03 |
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出版者 | ||||||
出版者 | Takasaki Advanced Radiation Research Institute, QST |