@article{oai:repo.qst.go.jp:00056020, author = {Kurosawa, Kakeru and Omoso, Kota and Takeshita, Hajime and 佐藤, 勝也 and 大野, 豊 and Narumi, Issay and 佐藤 勝也 and 大野 豊}, journal = {QST Takasaki Annual Report 2015}, month = {Mar}, note = {The genome analysis revealed that Deinococcus grandis possessed RDR regulon as shown in D. radiodurans. In this study, to delineate the function of PprA and PprI in radiation-induced DNA repair, we generated pprA and pprI deletion strains of D. grandis and investigated survivals of the deletion strains and wild type strains following exposure to gamma-rays. The D. grandis pprA deletion strain showed much higher sensitivity to gamma rays compared to the D. radiodurans pprA disruptant strain. On the other hand, the sensitivity of the D. grandis pprI deletion strain was comparable to that of D. radiodurans pprI deletion strain. The fact that the loss of pprA severely affected cell survival highlighted the functional importance of PprA protein in D. grandis.}, pages = {137--137}, title = {Functional Analysis of pprA and pprI Genes That Are Involved in Radiation/Desiccation Response in the Radioresistant Bacterium Deinococcus grandis}, year = {2017} }