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重粒子線治療の最適化のための生物学研究-Ｉ正常組織障害
https://repo.qst.go.jp/records/55412
https://repo.qst.go.jp/records/55412190f618c-6f8d-4a18-a1e5-35c8212c9006
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-11-04 | |||||
| タイトル | ||||||
| タイトル | 重粒子線治療の最適化のための生物学研究-Ｉ正常組織障害 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
高井, 伸彦
× 高井, 伸彦× 安藤, 興一× 古澤, 佳也× 鵜澤, 玲子× 小池, 幸子× 青木, 瑞穂× 扶川, 武志× 物部, 真奈美× 平山, 亮一× 渡邉, 雅彦× 高井 伸彦× 安藤 興一× 古澤 佳也× 鵜澤 玲子× 小池 幸子× 青木 瑞穂× 扶川 武志× 物部 真奈美× 平山 亮一× 渡邉 雅彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | This study evaluated the ability of 14C-Thymidine for detecting the early effects of irradiation on tissues proliferation-rate. Conditioning irradiation with 290 MeV/u carbon ions delivered to the tissues at 10 cm diameter. To measured 14C-Thymidine uptake, mice were intravenously injected with tracers. The significantly decrease in 14C-Thymidine uptake in gut and skin were observed 4 hours after carbon-beam irradiation. The 14C-Thymidine uptake in the skin was restarted at 4hr after irradiation. In contrast, 14C-Thymidine uptake in the gut was restarted 12hr after irradiation. These findings demonstrated that the thymidine uptake in vivo could be an appropriate marker for investigating tissues proliferation-activity after radiotherapy. Thymidine uptake could predict for or allow for rapid monitoring of response to radiation effects. | |||||
| 書誌情報 |
放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書 巻 2005, p. 82-83, 発行日 2005-05 |
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| 出版者 | ||||||
| 出版者 | 放医研 | |||||
