@article{oai:repo.qst.go.jp:00055412,
 author = {高井, 伸彦 and 安藤, 興一 and 古澤, 佳也 and 鵜澤, 玲子 and 小池, 幸子 and 青木, 瑞穂 and 扶川, 武志 and 物部, 真奈美 and 平山, 亮一 and 渡邉, 雅彦 and 高井 伸彦 and 安藤 興一 and 古澤 佳也 and 鵜澤 玲子 and 小池 幸子 and 青木 瑞穂 and 扶川 武志 and 物部 真奈美 and 平山 亮一 and 渡邉 雅彦},
 journal = {放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書},
 month = {May},
 note = {This study evaluated the ability of 14C-Thymidine for detecting the early effects of irradiation on tissues proliferation-rate. Conditioning irradiation with 290 MeV/u carbon ions delivered to the tissues at 10 cm diameter. To measured 14C-Thymidine uptake, mice were intravenously injected with tracers. The significantly decrease in 14C-Thymidine uptake in gut and skin were observed 4 hours after carbon-beam irradiation. The 14C-Thymidine uptake in the skin was restarted at 4hr after irradiation. In contrast, 14C-Thymidine uptake in the gut was restarted 12hr after irradiation. These findings demonstrated that the thymidine uptake in vivo could be an appropriate marker for investigating tissues proliferation-activity after radiotherapy. Thymidine uptake could predict for or allow for rapid monitoring of response to radiation effects.},
 pages = {82--83},
 title = {重粒子線治療の最適化のための生物学研究-Ｉ正常組織障害},
 volume = {2005},
 year = {2005}
}