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培養細胞による治療ビーム特性の検証と最適化に関する総合的開発研究
https://repo.qst.go.jp/records/55074
https://repo.qst.go.jp/records/55074e028a71a-2ecc-4db2-9ab5-69ae50eef5cd
| Item type | 一般雑誌記事 / Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2003-08-29 | |||||
| タイトル | ||||||
| タイトル | 培養細胞による治療ビーム特性の検証と最適化に関する総合的開発研究 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
古澤, 佳也
× 古澤, 佳也× 青木, 瑞穂× 香川, 一史× 村上, 昌雄× 安藤, 興一× 金井, 達明× 宮原, 信幸× 古澤 佳也× 青木 瑞穂× 香川 一史× 村上 昌雄× 安藤 興一× 金井 達明× 宮原 信幸 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | 1) Evaluation of RBE of a proton 190 MeV 60 mm SOBP beam and a carbon 320 MeV/u 60 mm SOBP beam, and the uniformity of biological dose in the spread-out part of the SOBP beam also has measured.by using HSG cells at a particle therapy facility in Hyogo-prefecture has performed as well as HIMAC. The RBE for the proton beams at different depth varied from 1.01 to 1.07 for all depth measured at 10% and 50% survival level, and the biological doses of the beam measured by the Cell-Stack chamber to an exposure of 3.3Gy showed approximately 30% of survival, and was also very uniform. 2) Evaluation of RBE at high dose region for the carbon 140 MeV/u 25 mm SOBP beam for eye-melanoma treatment at HIMAC has also performed. The RBE value measured by the HSG cells at 0.01% survival level varies ranging 1.66-1.87 at the proximal, middle, and distal positions of the SOBP. The value was very similar to that reported previously bu using HMV-I melanoma cells, also similar to an estimated value when the ridge filter was designed. An very sharp cut off of the penumbra was also determined by a biological Cell-Stack method. |
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| 書誌情報 |
放射線医学総合研究所重粒子線がん治療装置等共同利用研究報告書 巻 2001, p. 55-56, 発行日 2001-04 |
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| 出版者 | ||||||
| 出版者 | 放医研 | |||||
