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Redox Behavior of 2,2-Diphenyl-1-Picrylhydrazyl Radical (DPPH∙) Solubilized in Water by β-Cyclodextrin
https://repo.qst.go.jp/records/54790
https://repo.qst.go.jp/records/54790a09a8d52-0441-4557-91bd-e61dd32e144d
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-07-12 | |||||
| タイトル | ||||||
| タイトル | Redox Behavior of 2,2-Diphenyl-1-Picrylhydrazyl Radical (DPPH∙) Solubilized in Water by β-Cyclodextrin | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nakanishi, Ikuo
× Nakanishi, Ikuo× Ozawa, Toshihiko× Matsumoto, Kenichiro× 中西 郁夫× 小澤 俊彦× 松本 謙一郎 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | 2,2-Diphenyl-1-picrylhydrazyl radical (DPPH●) is a relatively stable radical and frequently used as a reactivity model of reactive oxygen species. However, its insolubility in water precludes the investigation of the redox behavior of DPPH● in aqueous media, especially in concentrated buffer solutions. We have recently reported that DPPH● can be successfully solubilized in water by β-cyclodextrin (β-CD). The as-obtained β-CD-solubilized DPPH● (DPPH●/β-CD) was demonstrated to be a powerful tool for evaluating the antioxidative activity of water-soluble antioxidants, such as ascorbic acid, Trolox, and caffeic acid, in concentrated buffer solutions. In this study, the redox behavior of DPPH●/β-CD was investigated by cyclic voltammetry. A well-defined reversible redox wave was observed for one-electron reduction of DPPH●/β-CD in phosphate buffer (0.1 M, pH 7.4). On the other hand, one-electron oxidation of DPPH●/β-CD showed a quasi-reversible redox wave, which suggests that DPPH cations (DPPH+) generated by the electrochemical one-electron oxidation may undergo a follow-up chemical reaction, such as an addition of a water molecule. | |||||
| 書誌情報 |
Free Radical Biology and Medicine 巻 100, 号 Supplement, p. S27-S28, 発行日 2016-11 |
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| 出版者 | ||||||
| 出版者 | Elsevier | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.freeradbiomed.2016.10.068 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://www.sciencedirect.com/science/article/pii/S0891584916305391 | |||||
| 関連名称 | http://www.sciencedirect.com/science/article/pii/S0891584916305391 | |||||
