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トビムシにおける放射線照射後のDNA修復関連遺伝子の発現
https://repo.qst.go.jp/records/54080
https://repo.qst.go.jp/records/54080a33840ae-d2f1-4701-beda-4a69549bcd9f
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-12-15 | |||||
| タイトル | ||||||
| タイトル | トビムシにおける放射線照射後のDNA修復関連遺伝子の発現 | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
中森, 泰三
× 中森, 泰三× 吉田, 聡× 久保田, 善久× 坂内, 忠明× 藤森, 亮× 中森 泰三× 吉田 聡× 久保田 善久× 坂内 忠明× 藤森 亮 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To develop biomarker of ionizing radiation exposure for the radiological protection of the environment, we examined dose-, age-, and time-dependences of the DNA repair-related gene expression after acute gamma irradiation in the springtail Folsomia candida. High-coverage expression profiling (HiCEP) was used to screening radiation-responsive genes in F. candida, and the identified genes included a poly(ADP-ribose) polymerase (PARP)-like gene. Expression of the PARP-like gene was up-regulated in a dose-dependent manner both in juveniles and adults. Levels of the up-regulation were higher in juveniles than in adults, and changed dramatically within 4 h after but a little 4–24 h after irradiation. In conclusion, expression of the PARP-like gene of F. candida may be used as a biomarker of radiation exposure if age-synchronized animals fixed 4–24 h after exposure were used. | |||||
| 書誌情報 |
Proceedings of the Workshop on Environmental Radioactivity (KEK Proceedings) 巻 2008-9, p. 29-31, 発行日 2008-11 |
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