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19F high senseitivity imaging for in vivo drug dynamics in mice at 7T with 5-FU
https://repo.qst.go.jp/records/53793
https://repo.qst.go.jp/records/537930e4bd967-6aec-4058-9569-8875763dfc44
Item type | 会議発表論文 / Conference Paper(1) | |||||
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公開日 | 2007-01-04 | |||||
タイトル | ||||||
タイトル | 19F high senseitivity imaging for in vivo drug dynamics in mice at 7T with 5-FU | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
資源タイプ | conference paper | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Kanazawa, Yoko
× Kanazawa, Yoko× Hirano, Yoshiyuki× Koike, Sachiko× Narazaki, Michiko× Yoshitome, Eiji× Ando, Koichi× Ikehira, Hiroo× et.al× 金沢 洋子× 平野 好幸× 小池 幸子× 楢崎 美智子× 吉留 英二× 安藤 興一× 池平 博夫 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The evaluation of drug efficacy and safety for individuals will become more reliable by performing direct dynamical study of drug itself. This is a study towards this purpose using 5-FU in animals. CSI is often used for the metabolite distribution. However, for the compounds with metabolites in wide range of chemical shift, generation of pulse covering sufficient band width is difficult for imaging instrument. One of the best methods for the dynamical study of 19F containing drug, e.g. 5-FU, has been found to be frequency selective imaging [1]. Here, we evaluate fast imaging sequences including FISP and Flash in comparison to FSE at 7T. | |||||
書誌情報 |
Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 巻 14, p. 3094, 発行日 2006 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1524-6965 |