@inproceedings{oai:repo.qst.go.jp:00053793, author = {Kanazawa, Yoko and Hirano, Yoshiyuki and Koike, Sachiko and Narazaki, Michiko and Yoshitome, Eiji and Ando, Koichi and Ikehira, Hiroo and et.al and 金沢 洋子 and 平野 好幸 and 小池 幸子 and 楢崎 美智子 and 吉留 英二 and 安藤 興一 and 池平 博夫}, book = {Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition}, month = {}, note = {The evaluation of drug efficacy and safety for individuals will become more reliable by performing direct dynamical study of drug itself. This is a study towards this purpose using 5-FU in animals. CSI is often used for the metabolite distribution. However, for the compounds with metabolites in wide range of chemical shift, generation of pulse covering sufficient band width is difficult for imaging instrument. One of the best methods for the dynamical study of 19F containing drug, e.g. 5-FU, has been found to be frequency selective imaging [1]. Here, we evaluate fast imaging sequences including FISP and Flash in comparison to FSE at 7T.}, title = {19F high senseitivity imaging for in vivo drug dynamics in mice at 7T with 5-FU}, volume = {14}, year = {2006} }