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Effects of Heavy Ion to the Primary Culture of Mouse Brain Cells
https://repo.qst.go.jp/records/53497
https://repo.qst.go.jp/records/53497f8dc892c-f26b-41d7-adde-115f6dd8e405
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2005-02-14 | |||||
| タイトル | ||||||
| タイトル | Effects of Heavy Ion to the Primary Culture of Mouse Brain Cells | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nojima, Kumie
× Nojima, Kumie× Nakadai, Taeko× Kouno, Yukio× E., Vazquez Marcelo× Yasuda, Nakahiro× Nagaoka, Shunji× 野島 久美恵× 中台 妙子× 河野 幸雄× 安田 仲宏× 長岡 俊治 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | To investigate effects of low dose heavy particle radiation to CNS system , we adopted mouse neonatal brain cells in culture being exposed to heavy ion by HIMAC at NIRS and NSRL at BNL. The applied dose varied from 0,05 Gy up to 2.0 Gy. The subsequent biological effects were evaluated by an induction of apoptosis and neuron survival focusing on the dependencies of the animal strains, SCID, B6, BC3F1, C3H, used for brain cell culture, SCID was the most sensitive and C3H the least sensitive to particle radiation as evaluated by 10% apoptotic criterion. The LET dependency was compared with using SCID and B6 cells exposing to different ions (H, C, Ne, Si, Ar, and Fe). Although no detectable LET dependency was observed in the high LET (55~200KeV/mm) and low dose (<0.5 Gy) reasions. The survivability profiles of the neurons were different in the mouse strains and ions. | |||||
| 書誌情報 |
Biological Sciences in Space 巻 18, p. 114-115, 発行日 2004-11 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0914-9201 | |||||
