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Chromosome analysis in three patients.
https://repo.qst.go.jp/records/53255
https://repo.qst.go.jp/records/53255b1d0718b-125d-4e19-b481-fff07923bee3
| Item type | 会議発表論文 / Conference Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2003-11-18 | |||||
| タイトル | ||||||
| タイトル | Chromosome analysis in three patients. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||
| 資源タイプ | conference paper | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Hayata, Isamu
× Hayata, Isamu× Kanda, Reiko× Minamihisamatsu, Masako× Furukawa, Akira× Sasaki, Masao× 早田 勇× 神田 玲子× 南久松 眞子× 古川 章× 佐々木 正夫 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Dose estimation for the 3 severely exposed cases was performed by chromosome analysis. The whole body dose of radiation they had been exposed to was an unprecedented much higher dose than we had encountered in previous radiation accidents. The rate of lymphocytes in the white blood cells in two of the cases was so low that we could not culture and harvest cells by the conventional method. We took two specific measures to break through this difficulty. First, to collect a sufficient number of lymphocytes necessary for chromosome preparation, we processed blood samples by a modified method called the high-yield chromosome preparation method. Secondly, the dose estimation was made by two methods: a new method of scoring the PCC-ring and an ordinary dicentric and ring chromosome (Dic+R) counting method. The quickly but crudely obtained result by the former was in good agreement with the result obtained by the more time-consuming but well established latter method. The biologically estimated dose was comparable with the dose estimated by the physical method. As far as we know, the estimated dose of the most severely exposed case in the present study is the highest known record to date of dose chromosome analyses could assess in human radiation exposures. | |||||
| 書誌情報 |
International Symposium on the Criticality Accident in Tokaimura : Medical Aspects of Radiation Emergency : Proceedings p. 82-89, 発行日 2000 |
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| 出版者 | ||||||
| 出版者 | National Institute of Radiological Sciences | |||||
