@inproceedings{oai:repo.qst.go.jp:00053255,
 author = {Hayata, Isamu and Kanda, Reiko and Minamihisamatsu, Masako and Furukawa, Akira and Sasaki, Masao and 早田 勇 and 神田 玲子 and 南久松 眞子 and 古川 章 and 佐々木 正夫},
 book = {International Symposium on the Criticality Accident in Tokaimura : Medical Aspects of Radiation Emergency : Proceedings},
 month = {},
 note = {Dose estimation for the 3 severely exposed cases was performed by chromosome analysis. The whole body dose of radiation they had been exposed to was an unprecedented much higher dose than we had encountered in previous radiation accidents. The rate of lymphocytes in the white blood cells in two of the cases was so low that we could not culture and harvest cells by the conventional method. We took two specific measures to break through this difficulty. First, to collect a sufficient number of lymphocytes necessary for chromosome preparation, we processed blood samples by a modified method called the high-yield chromosome preparation method. Secondly, the dose estimation was made by two methods: a new method of scoring the PCC-ring and an ordinary dicentric and ring chromosome (Dic+R) counting method. The quickly but crudely obtained result by the former was in good agreement with the result obtained by the more time-consuming but well established latter method. The biologically estimated dose was comparable with the dose estimated by the physical method. As far as we know, the estimated dose of the most severely exposed case in the present study is the highest known record to date of dose chromosome analyses could assess in human radiation exposures.},
 pages = {82--89},
 publisher = {National Institute of Radiological Sciences},
 title = {Chromosome analysis in three patients.},
 year = {2000}
}