WEKO3
アイテム
{"_buckets": {"deposit": "905f456a-da6b-485d-8418-b0e88f349e11"}, "_deposit": {"created_by": 1, "id": "49585", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "49585"}, "status": "published"}, "_oai": {"id": "oai:repo.qst.go.jp:00049585", "sets": ["1"]}, "author_link": ["759930", "759931", "759936", "759932", "759935", "759933", "759934", "759929"], "item_8_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-08", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "138", "bibliographicPageStart": "133-", "bibliographicVolumeNumber": "308", "bibliographic_titles": [{"bibliographic_title": "Biochemical and biophysical research communications"}]}]}, "item_8_description_5": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The aim of this study was to gain insight into early events in the lung epithelial cells following acute Cd exposure. We adopted the polymerase chain reaction (PCR)-based subtraction technique and found several genes that were upregulated in immortalized rat lung type 2 epithelial cells (SV40T2). The upregulation of those genes was confirmed by Northern blot analysis and categorized into three groups (highly, moderately, and weakly inducible genes). Heme oxygenase-1 (HO-1), HSP 72, hepatic steroid hydroxylase/CYPIIA2, and Cd-inducible gene 1 (cdig1, a new gene, Accession Nos. AB086233 and AB086234) were highly inducible genes, testosterone-repressed prostate message 2 mRNA was moderately inducible, and collagen-binding protein and cdig2 (another new gene, Accession No. AB086193) mRNAs were weakly inducible. The expression of cdig1 increased linearly with time up to 9h, while that of HO-1 reached the maximum value at 4h in response to 10 microM Cd.", "subitem_description_type": "Abstract"}]}, "item_8_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier"}]}, "item_8_relation_13": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "12890491", "subitem_relation_type_select": "PMID"}}]}, "item_8_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "0006-291X", "subitem_source_identifier_type": "ISSN"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "metadata only access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_14cb"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Hirano, Seishiro"}], "nameIdentifiers": [{"nameIdentifier": "759929", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kitajima, Hiroki"}], "nameIdentifiers": [{"nameIdentifier": "759930", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Hayakawa, Toru"}], "nameIdentifiers": [{"nameIdentifier": "759931", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Cui, Xing"}], "nameIdentifiers": [{"nameIdentifier": "759932", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kanno, Sanae"}], "nameIdentifiers": [{"nameIdentifier": "759933", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kobayashi, Yayoi"}], "nameIdentifiers": [{"nameIdentifier": "759934", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Megumi"}], "nameIdentifiers": [{"nameIdentifier": "759935", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sai, Sei", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "759936", "nameIdentifierScheme": "WEKO"}]}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells.", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells."}]}, "item_type_id": "8", "owner": "1", "path": ["1"], "permalink_uri": "https://repo.qst.go.jp/records/49585", "pubdate": {"attribute_name": "公開日", "attribute_value": "2019-02-09"}, "publish_date": "2019-02-09", "publish_status": "0", "recid": "49585", "relation": {}, "relation_version_is_last": true, "title": ["PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells."], "weko_shared_id": -1}
PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells.
https://repo.qst.go.jp/records/49585
https://repo.qst.go.jp/records/495856ab5003d-4693-49b3-b865-f154ac25f14f
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2019-02-09 | |||||
タイトル | ||||||
タイトル | PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Hirano, Seishiro
× Hirano, Seishiro× Kitajima, Hiroki× Hayakawa, Toru× Cui, Xing× Kanno, Sanae× Kobayashi, Yayoi× Yamamoto, Megumi× Sai, Sei |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The aim of this study was to gain insight into early events in the lung epithelial cells following acute Cd exposure. We adopted the polymerase chain reaction (PCR)-based subtraction technique and found several genes that were upregulated in immortalized rat lung type 2 epithelial cells (SV40T2). The upregulation of those genes was confirmed by Northern blot analysis and categorized into three groups (highly, moderately, and weakly inducible genes). Heme oxygenase-1 (HO-1), HSP 72, hepatic steroid hydroxylase/CYPIIA2, and Cd-inducible gene 1 (cdig1, a new gene, Accession Nos. AB086233 and AB086234) were highly inducible genes, testosterone-repressed prostate message 2 mRNA was moderately inducible, and collagen-binding protein and cdig2 (another new gene, Accession No. AB086193) mRNAs were weakly inducible. The expression of cdig1 increased linearly with time up to 9h, while that of HO-1 reached the maximum value at 4h in response to 10 microM Cd. | |||||
書誌情報 |
Biochemical and biophysical research communications 巻 308, 号 1, p. 133--138, 発行日 2018-08 |
|||||
出版者 | ||||||
出版者 | Elsevier | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0006-291X | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 12890491 |