{"created":"2023-05-15T14:38:25.104238+00:00","id":49585,"links":{},"metadata":{"_buckets":{"deposit":"905f456a-da6b-485d-8418-b0e88f349e11"},"_deposit":{"created_by":1,"id":"49585","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"49585"},"status":"published"},"_oai":{"id":"oai:repo.qst.go.jp:00049585","sets":["1"]},"author_link":["759930","759931","759936","759932","759935","759933","759934","759929"],"item_8_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-08","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"138","bibliographicPageStart":"133-","bibliographicVolumeNumber":"308","bibliographic_titles":[{"bibliographic_title":"Biochemical and biophysical research communications"}]}]},"item_8_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The aim of this study was to gain insight into early events in the lung epithelial cells following acute Cd exposure. We adopted the polymerase chain reaction (PCR)-based subtraction technique and found several genes that were upregulated in immortalized rat lung type 2 epithelial cells (SV40T2). The upregulation of those genes was confirmed by Northern blot analysis and categorized into three groups (highly, moderately, and weakly inducible genes). Heme oxygenase-1 (HO-1), HSP 72, hepatic steroid hydroxylase/CYPIIA2, and Cd-inducible gene 1 (cdig1, a new gene, Accession Nos. AB086233 and AB086234) were highly inducible genes, testosterone-repressed prostate message 2 mRNA was moderately inducible, and collagen-binding protein and cdig2 (another new gene, Accession No. AB086193) mRNAs were weakly inducible. The expression of cdig1 increased linearly with time up to 9h, while that of HO-1 reached the maximum value at 4h in response to 10 microM Cd.","subitem_description_type":"Abstract"}]},"item_8_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_8_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"12890491","subitem_relation_type_select":"PMID"}}]},"item_8_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0006-291X","subitem_source_identifier_type":"ISSN"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"metadata only access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_14cb"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hirano, Seishiro"}],"nameIdentifiers":[{"nameIdentifier":"759929","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kitajima, Hiroki"}],"nameIdentifiers":[{"nameIdentifier":"759930","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Hayakawa, Toru"}],"nameIdentifiers":[{"nameIdentifier":"759931","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Cui, Xing"}],"nameIdentifiers":[{"nameIdentifier":"759932","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kanno, Sanae"}],"nameIdentifiers":[{"nameIdentifier":"759933","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kobayashi, Yayoi"}],"nameIdentifiers":[{"nameIdentifier":"759934","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Yamamoto, Megumi"}],"nameIdentifiers":[{"nameIdentifier":"759935","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sai, Sei","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"759936","nameIdentifierScheme":"WEKO"}]}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells."}]},"item_type_id":"8","owner":"1","path":["1"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-02-09"},"publish_date":"2019-02-09","publish_status":"0","recid":"49585","relation_version_is_last":true,"title":["PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells."],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-05-16T00:44:27.987969+00:00"}