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Two cases of pelvic sarcoma in the acetabulum with >10-year follow-ups after carbon ion radiotherapy.
https://repo.qst.go.jp/records/48955
https://repo.qst.go.jp/records/48955f572546b-0f59-4bc4-8d69-e4a9609e27af
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-05-11 | |||||
| タイトル | ||||||
| タイトル | Two cases of pelvic sarcoma in the acetabulum with >10-year follow-ups after carbon ion radiotherapy. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
kawanami, Katsuhisa
× kawanami, Katsuhisa× matsuo, Toshihiro× sato, Keiji× Imai, Reiko× kamiya, Mitsuhiro× wakao, Norimitsu× hirasawa, Atsuhiko× deie, Masataka× 今井 礼子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | There are many cases of bone and soft-tissue sarcoma in which resection is difficult. This difficulty is typically related to the lesion's original location or the possibility that resection could lead to a marked decline in the patient's quality of life, based on postoperative motor dysfunction or neurological damage [1]. Moreover, even in cases where resection is possible, postoperative irradiation is recommended for patients who experience incomplete resection or exhibit positive surgical margins. However, many kinds of bone and soft-tissue sarcomas are radio-resistant tumours, and it is can be difficult to control them using X-ray radiation therapy. In the field of radiation oncology, heavy-ion beams are defined as radiation that is obtained by accelerating charged nuclei that are heavier than protons. Carbon ion radiotherapy is one type of heavyion radiotherapy having potential advantages over conventional radiotherapy [2]. For example, carbon ions provide better physical dose distribution, compared to conventional radiotherapy, because of the special characteristic of charged particle beams (the Bragg peak) [2,3]. Furthermore, they have a higher relative biological effectiveness and a lower oxygen enhancement ratio. Some researchers have argued that protons represent a technical improvement for highly conformal therapy, and that heavier ions might even facilitate the treatment of cancers that are resistant to conventional X-ray therapy [4]. In Japan, the National Institute of Radiological Science (NIRS) has treated patients using carbon ion radiotherapy since 1994, and over 8000 patients with various solid tumours have been treated using by carbon ion radiotherapy at NIRS [2]. We informed two patients that there are not only advantages of surgery but also postoperative complications. In addition, we told them that carbon ion radiotherapy might be a safe and effective modality for patients who localized primary sarcoma who are unsuitable for resection or for patients who refuse surgery including amputation. As a result, both of them made a choose carbon ion therapy. In the present report, we describe two cases of pelvic sarcomas with available oncological and functional results from prolonged follow-ups (>10 years) after carbon ion radiotherapy without surgery. Informed consent has been obtained from these two patients for publication. This is the first report regarding delayed side effects of carbon ion radiotherapy after a long-term follow-up. |
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| 書誌情報 |
Journal of Orthopaedic Science 巻 S0949-2658, 号 17, p. 30192-30196, 発行日 2017-08 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0949-2658 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 28818569 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.jos.2017.08.003 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | www.elsevier.com/locate/jos | |||||
| 関連名称 | www.elsevier.com/locate/jos | |||||
