WEKO3
アイテム
Anatomical relationships between serotonin 5-HT2A and dopamine D2 receptors in living human brain
https://repo.qst.go.jp/records/48803
https://repo.qst.go.jp/records/48803986899e1-dce3-4feb-9673-42179558de90
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-04-24 | |||||
| タイトル | ||||||
| タイトル | Anatomical relationships between serotonin 5-HT2A and dopamine D2 receptors in living human brain | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ishii, Tatsuya
× Ishii, Tatsuya× Kimura, Yasuyuki× Ichise, Masanori× Takahata, Keisuke× Kitamura, Soichiro× Moriguchi, Sho× Kubota, Manabu× Zhang, Ming-Rong× Yamada, Makiko× Higuchi, Makoto× Okubo, Yoshinori× Suhara, Tetsuya× 石井 辰弥× 木村 泰之× 市瀬 正則× 高畑 圭輔× 北村 聡一郎× 森口 翔× 久保田 学× 張 明栄× 山田 真希子× 樋口 真人× 須原 哲也 |
|||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Serotonin 2A (5-HT2A) receptors and dopamine D2 receptors are intimately related to the physiology and pathophysiology of neuropsychiatric disorders. A large number of studies have reported the effectiveness of psychotropic agents targeting 5-HT2A and D2 receptors in these disorders. In addition to the individual functions of these receptors, the interaction between the two neurotransmitter systems has been studied in the living brain. However, little is known about their regional relationship in individual human brains. We investigated regional relationships between 5-HT2A and D2 receptors using positron emission tomography (PET) and a bicluster analysis of the correlation matrix of individual variation in the two receptor densities to identify groups of distinctive regional correlations between the two receptors. |
|||||
| 書誌情報 |
PLOS ONE 巻 12, 号 12, p. e0189318, 発行日 2017-12 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1932-6203 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 29220382 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1371/journal.pone.0189318 | |||||
