@article{oai:repo.qst.go.jp:00048803, author = {Ishii, Tatsuya and Kimura, Yasuyuki and Ichise, Masanori and Takahata, Keisuke and Kitamura, Soichiro and Moriguchi, Sho and Kubota, Manabu and Zhang, Ming-Rong and Yamada, Makiko and Higuchi, Makoto and Okubo, Yoshinori and Suhara, Tetsuya and 石井 辰弥 and 木村 泰之 and 市瀬 正則 and 高畑 圭輔 and 北村 聡一郎 and 森口 翔 and 久保田 学 and 張 明栄 and 山田 真希子 and 樋口 真人 and 須原 哲也}, issue = {12}, journal = {PLOS ONE}, month = {Dec}, note = {Serotonin 2A (5-HT2A) receptors and dopamine D2 receptors are intimately related to the physiology and pathophysiology of neuropsychiatric disorders. A large number of studies have reported the effectiveness of psychotropic agents targeting 5-HT2A and D2 receptors in these disorders. In addition to the individual functions of these receptors, the interaction between the two neurotransmitter systems has been studied in the living brain. However, little is known about their regional relationship in individual human brains. We investigated regional relationships between 5-HT2A and D2 receptors using positron emission tomography (PET) and a bicluster analysis of the correlation matrix of individual variation in the two receptor densities to identify groups of distinctive regional correlations between the two receptors.}, title = {Anatomical relationships between serotonin 5-HT2A and dopamine D2 receptors in living human brain}, volume = {12}, year = {2017} }