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Analysis of Redox States of Protic and Aprotic Solutions Irradiated by Low Linear Energy Transfer Carbon-Ion Beams Using a 2,2-Diphenyl-1-picrylhydrazyl Radical
https://repo.qst.go.jp/records/48794
https://repo.qst.go.jp/records/48794116ac8b3-1cb9-4f85-bc12-5df5ee1c35c3
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2018-04-23 | |||||
| タイトル | ||||||
| タイトル | Analysis of Redox States of Protic and Aprotic Solutions Irradiated by Low Linear Energy Transfer Carbon-Ion Beams Using a 2,2-Diphenyl-1-picrylhydrazyl Radical | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Nakanishi, Ikuo
× Nakanishi, Ikuo× Yamashita, Shinichi× Shimokawa, Takashi× Kamibayashi, Masato× Sekine-Suzuki, Emiko× Ueno, Megumi× Ogawa, Yukihiro× Ozawa, Toshihiko× Matsumoto, Ken-ichiro× 中西 郁夫× 山下 真一× 下川 卓志× 上林 將人× 関根 絵美子× 上野 恵美× 小川 幸大× 小澤 俊彦× 松本 謙一郎 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The quantitative evaluation of changes in the redox state induced by low linear energy transfer (LET) radiations, such as the plateau region of heavy-ion beams, via formation of reactive oxygen species is of considerable importance to eliminate the adverse effects of radiation therapy on normal tissues adjacent to the tumour. In this study, a 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical was used as a redox probe to estimate the redox states of protic and aprotic solutions irradiated by low LET carbon-ion (C-ion) beams. The dose dependence of the decrease in the absorption band due to DPPH radial, which was solubilised by β-cyclodextrin (β-CD) in water, after irradiation with low LET C-ion beams (13 keV/µm) is similar to that after X-irradiation. Similar results were obtained when H2O was replaced with methanol or acetonitrile, although the slope values of the plots of the absorbance changes vs. radiation doses are twice larger compared to the case in β-CD-containing H2O. On the other hand, DPPH radical was more susceptible to the C-ion beam than to X-ray in isopropyl myristate (IPM), one of saturated fatty acid esters. | |||||
| 書誌情報 |
Organic & Biomolecular Chemistry 巻 16, 号 8, p. 1272-1276, 発行日 2018-01 |
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| 出版者 | ||||||
| 出版者 | The Royal Society of Chemistry | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1477-0520 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 29384168 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1039/C7OB02904G | |||||
