@article{oai:repo.qst.go.jp:00048794,
 author = {Nakanishi, Ikuo and Yamashita, Shinichi and Shimokawa, Takashi and Kamibayashi, Masato and Sekine-Suzuki, Emiko and Ueno, Megumi and Ogawa, Yukihiro and Ozawa, Toshihiko and Matsumoto, Ken-ichiro and 中西 郁夫 and 山下 真一 and 下川 卓志 and 上林 將人 and 関根 絵美子 and 上野 恵美 and 小川 幸大 and 小澤 俊彦 and 松本 謙一郎},
 issue = {8},
 journal = {Organic & Biomolecular Chemistry},
 month = {Jan},
 note = {The quantitative evaluation of changes in the redox state induced by low linear energy transfer (LET) radiations, such as the plateau region of heavy-ion beams, via formation of reactive oxygen species is of considerable importance to eliminate the adverse effects of radiation therapy on normal tissues adjacent to the tumour.   In this study, a 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical was used as a redox probe to estimate the redox states of protic and aprotic solutions irradiated by low LET carbon-ion (C-ion) beams.  The dose dependence of the decrease in the absorption band due to DPPH radial, which was solubilised by β-cyclodextrin (β-CD) in water, after irradiation with low LET C-ion beams (13 keV/µm) is similar to that after X-irradiation.  Similar results were obtained when H2O was replaced with methanol or acetonitrile, although the slope values of the plots of the absorbance changes vs. radiation doses are twice larger compared to the case in β-CD-containing H2O.  On the other hand, DPPH radical was more susceptible to the C-ion beam than to X-ray in isopropyl myristate (IPM), one of saturated fatty acid esters.},
 pages = {1272--1276},
 title = {Analysis of Redox States of Protic and Aprotic Solutions Irradiated by Low Linear Energy Transfer Carbon-Ion Beams Using a 2,2-Diphenyl-1-picrylhydrazyl Radical},
 volume = {16},
 year = {2018}
}