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New silicon microdosimetry probes for RBE and biological dose studies using stationary and movable targets in 12C ion therapy
https://repo.qst.go.jp/records/48172
https://repo.qst.go.jp/records/4817247848ea6-f34c-4674-a6a4-c6ab0419aea9
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-07-24 | |||||
| タイトル | ||||||
| タイトル | New silicon microdosimetry probes for RBE and biological dose studies using stationary and movable targets in 12C ion therapy | |||||
| 言語 | ||||||
| 言語 | jpn | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Ｃｈａｒｔｉｅｒ, Ｌａｃｈｌａｎ
× Ｃｈａｒｔｉｅｒ, Ｌａｃｈｌａｎ× Ｔｒａｎ, Ｔｈｕｙ Ｌｉｎｈ× ＢＯＬＳＴ, Ｄａｖｉｄ× Pogossov, A× Guatelli, S× Petasecca, M× Lerch, M× Ｐｒｏｋｏｐｏｖｉｃｈ, Ａｎｔｈｏｎｙ× Reinhard, M× Perevertaylo, V× Jackson, M× 松藤, 成弘× B, Rosenfeld A× Ｃｈａｒｔｉｅｒ Ｌａｃｈｌａｎ× Ｔｒａｎ Ｔｈｕｙ Ｌｉｎｈ× ＢＯＬＳＴ Ｄａｖｉｄ× Ｐｒｏｋｏｐｏｖｉｃｈ Ａｎｔｈｏｎｙ× 松藤 成弘 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Due to the high LET and dense ionisation tracks associated with ions, microdosimetric approaches have been used in carbon ion therapy to assess field quality and calculate radiobiological quantities for a variety of cell lines. There is however a lack of instrumentation for simple and routine use in a clinical environment, important for determination of RBE which provides accurate treatment planning and delivery in hadron therapy. In this study, a 10 μm thick silicon microdosimeter with 3D sensitive volumes has been used to investigate the effect of motion on the RBE and field quality of a typical 12C ion therapy beam. For a passively scattered 290 MeV/u 12C beam with 6 cm spread-out Bragg peak (SOBP), variations in biological dose along the SOBP were observed, as well as a significant changes to particle LET when incident on a moving target. |
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| 書誌情報 |
Journal of Physics. Conference Series 巻 777, 号 1, p. 012019-1-012019-4, 発行日 2017-03 |
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| 出版者 | ||||||
| 出版者 | IOP Publishing | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1088/1742-6596/777/1/012019 | |||||
