@article{oai:repo.qst.go.jp:00048172, author = {Chartier, Lachlan and Tran, Thuy Linh and BOLST, David and Pogossov, A and Guatelli, S and Petasecca, M and Lerch, M and Prokopovich, Anthony and Reinhard, M and Perevertaylo, V and Jackson, M and 松藤, 成弘 and B, Rosenfeld A and Chartier Lachlan and Tran Thuy Linh and BOLST David and Prokopovich Anthony and 松藤 成弘}, issue = {1}, journal = {Journal of Physics. Conference Series}, month = {Mar}, note = {Due to the high LET and dense ionisation tracks associated with ions, microdosimetric approaches have been used in carbon ion therapy to assess field quality and calculate radiobiological quantities for a variety of cell lines. There is however a lack of instrumentation for simple and routine use in a clinical environment, important for determination of RBE which provides accurate treatment planning and delivery in hadron therapy. In this study, a 10 μm thick silicon microdosimeter with 3D sensitive volumes has been used to investigate the effect of motion on the RBE and field quality of a typical 12C ion therapy beam. For a passively scattered 290 MeV/u 12C beam with 6 cm spread-out Bragg peak (SOBP), variations in biological dose along the SOBP were observed, as well as a significant changes to particle LET when incident on a moving target.}, pages = {012019-1--012019-4}, title = {New silicon microdosimetry probes for RBE and biological dose studies using stationary and movable targets in 12C ion therapy}, volume = {777}, year = {2017} }