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Uranium XAFS analysis of kidney from rats exposed to uranium
https://repo.qst.go.jp/records/48149
https://repo.qst.go.jp/records/4814942731021-e06c-4f82-8bb8-38dc9635455d
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-07-24 | |||||
| タイトル | ||||||
| タイトル | Uranium XAFS analysis of kidney from rats exposed to uranium | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Kitahara, Keisuke
× Kitahara, Keisuke× Numako, Chiya× Terada, Yasuko× Nitta, Kiyofumi× Shimada, Yoshiya× Homma-Takeda, Shino× 島田 義也× 武田 志乃 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | AbstractThe kidney is the critical target of uranium exposure because uranium accumulates in the proximal tubules and causes tubular damage, but the chemical nature of uranium in kidney, such as its chemical status in the toxic target site, is poorly understood. Micro-X-ray absorption fine structure (μXAFS) analysis was used to examine renal thin sections of rats exposed to uranyl acetate. The U LIII-edge XANES spectra of bulk renal specimens obtained at various toxicological phases were similar to that of uranyl acetate: their edge position did not shift compared with that of uranyl acetate (17.175 keV) although the peak widths for some kidney specimens were slight narrowed. μXAFS measurements of spots of concentrated uranium in the micro-regions of the proximal tubules showed that the edge jump slightly shifted to lower energy. The results suggest that most uranium accumulated in kidney was uranium (VI) but a portion might have been biotransformed in rats exposed to uranyl acetate. | |||||
| 書誌情報 |
Journal of Synchrotron Radiation 巻 24, p. 456-462, 発行日 2017-03 |
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| 出版者 | ||||||
| 出版者 | IUCr Journals | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1107/S1600577517001850 | |||||
