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Structure Change from β-Strand and Turn to α-Helix in Histone H2A-H2B Induced by DNA Damage Response.
https://repo.qst.go.jp/records/47930
https://repo.qst.go.jp/records/479301bd1edf6-c89c-4411-a6fa-6300f4c70afc
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-05-01 | |||||
| タイトル | ||||||
| タイトル | Structure Change from β-Strand and Turn to α-Helix in Histone H2A-H2B Induced by DNA Damage Response. | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Izumi, Yudai
× Izumi, Yudai× Fujii, Kentaro× Wien, Frank× Houée-Lévin, Chantal× Lacombe, Sandrine× Salado-Leza, Daniela× Porcel, Erika× Masoud, Rawand× Yamamoto, Satoshi× Réfrégiers, Matthieu× Hervé, du Penhoat Marie-Anne× Yokoya, Akinari× 藤井 健太郎× 山本 悟史× 横谷 明徳 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Using synchrotron radiation-based circular dichroism spectroscopy, we found that the DNA damage response induces an increase of α-helix structure and a decrease of β-strand and turn structures in histone H2A-H2B extracted from x-irradiated human HeLa cells. The structural alterations correspond to the assumption that an average of eight amino acid residues form new α-helix structures at 310 K. We propose the structural transition from β-strand and turn structures to an α-helix structure in H2A-H2B as a novel, to our knowledge, process involved in the DNA damage response. | |||||
| 書誌情報 |
Biophysical journal 巻 111, 号 1, p. 69-78, 発行日 2016-07 |
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| 出版者 | ||||||
| 出版者 | Cell Press | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 27410735 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.bpj.2016.06.002 | |||||
