@article{oai:repo.qst.go.jp:00047930, author = {Izumi, Yudai and Fujii, Kentaro and Wien, Frank and Houée-Lévin, Chantal and Lacombe, Sandrine and Salado-Leza, Daniela and Porcel, Erika and Masoud, Rawand and Yamamoto, Satoshi and Réfrégiers, Matthieu and Hervé, du Penhoat Marie-Anne and Yokoya, Akinari and 藤井 健太郎 and 山本 悟史 and 横谷 明徳}, issue = {1}, journal = {Biophysical journal}, month = {Jul}, note = {Using synchrotron radiation-based circular dichroism spectroscopy, we found that the DNA damage response induces an increase of α-helix structure and a decrease of β-strand and turn structures in histone H2A-H2B extracted from x-irradiated human HeLa cells. The structural alterations correspond to the assumption that an average of eight amino acid residues form new α-helix structures at 310 K. We propose the structural transition from β-strand and turn structures to an α-helix structure in H2A-H2B as a novel, to our knowledge, process involved in the DNA damage response.}, pages = {69--78}, title = {Structure Change from β-Strand and Turn to α-Helix in Histone H2A-H2B Induced by DNA Damage Response.}, volume = {111}, year = {2016} }