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Biliary excretion of essential trace elements in rats under oxidative stress caused by selenium deficiency
https://repo.qst.go.jp/records/47548
https://repo.qst.go.jp/records/47548c7ced435-6199-4177-896f-8b70232765f7
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2015-08-15 | |||||
| タイトル | ||||||
| タイトル | Biliary excretion of essential trace elements in rats under oxidative stress caused by selenium deficiency | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Yamasaki, Kosuke
× Yamasaki, Kosuke× Sakuma, Yasunobu× Sasaki, Junya× Ken-ichiro, Matsumoto× Anzai, Kazunori× Matsuoka, Keisuke× Honda, Chikako× Tsukada, Masamichi× Endo, Kazutoyo× Enomoto, Shuichi× Matsumoto, Kenichiro× Anzai, Kazunori |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The excretion of essential trace elements, namely, Se, Sr, As, Mn, Co, V, Fe, and Zn into the bile of Se-deficient (SeD) Wistar male rats was studied using the multitracer (MT) technique, and instrumental neutron activation analysis (INAA). Normal and Se-control (SeC) rat groups were used as reference groups to compare the effects of Se levels on the behaviors of the essential trace elements. The excretion (% dose) of Se, Sr, As, Mn, Co, and V increased with Se levels in the liver. The biliary excretion of Mn and As dramatically enhanced for SeC rats compared with SeD rats, while that of V accelerated a little for SeC rats. The radioactivity levels of Fe-59 and Zn-65 in the MT tracer solution were insufficient to measure their excretion into bile. The role of glutathione and bilirubin for biliary excretion of the metals was discussed in relation to Se levels in rat liver. | |||||
| 書誌情報 |
Analytical and Bioanalytical Chemistry 巻 401, 号 8, p. 2531-2538, 発行日 2011-11 |
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| 出版者 | ||||||
| 出版者 | Springer-Verlag | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1618-2642 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1007/s00216-011-5333-4 | |||||
