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Carbon Ion Radiotherapy for Head and Neck Cancer
https://repo.qst.go.jp/records/46991
https://repo.qst.go.jp/records/469915b6afa34-d25c-41d5-b2a9-e222c6b0e7bb
Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-12-16 | |||||
タイトル | ||||||
タイトル | Carbon Ion Radiotherapy for Head and Neck Cancer | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
アクセス権 | ||||||
アクセス権 | metadata only access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
著者 |
Koto, Masashi
× Koto, Masashi× Hasegawa, Azusa× Takagi, Ryo× Ikawa, Hiroaki× Kamada, Tadashi× 小藤 昌志× 長谷川 安都佐× 高木 亮× 伊川 裕明× 鎌田 正 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Radiotherapy (RT) is a definitive treatment option for cancers of the head and neck. Indeed, the most common pathology of head and neck lesions, Squamous Cell Carcinoma (SCC), is radiosensitive. Recently, RT with chemotherapy has been shown to improve the local control and survival rates among patients with head and neck SCC. However, tumors arising in the head and neck region are of a variety of histological types, including adenoid cystic carcinoma, mucosal malignant melanoma, and bone and soft tissue sarcoma. Most of these tumors are resistant to RT, and therefore, RT is limited to postoperative or palliative care for these tumors. Carbon ions offer a biological advantage because, as compared with photons, carbon ions have higher linear energy transfer components in the Bragg peak. Carbon ions also provide a higher degree of physical selectivity because they have a finite range in tissue. Therefore, carbon ion RT permits better dose conformity than can be obtained with photon RT. Consequently, carbon ion RT can potentially control radio-resistant tumors while sparing normal tissues. This review summarizes clinical studies of carbon ion radiotherapy for head and neck cancers, especially non-SCCs. |
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書誌情報 |
Jounal of Radiology & Radiation Therapy 巻 2, 号 2, p. 1044, 発行日 2014-09 |
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出版者 | ||||||
出版者 | SciMed Central |