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  1. 原著論文

Vessel specific imaging of glucose transfer with fluorescent glucose analogue in anesthetized mouse cortex.

https://repo.qst.go.jp/records/46988
https://repo.qst.go.jp/records/46988
fd2cc191-7d23-48d6-9db0-68c3ca3024fc
Item type 学術雑誌論文 / Journal Article(1)
公開日 2014-12-16
タイトル
タイトル Vessel specific imaging of glucose transfer with fluorescent glucose analogue in anesthetized mouse cortex.
言語
言語 eng
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
アクセス権
アクセス権 metadata only access
アクセス権URI http://purl.org/coar/access_right/c_14cb
著者 Murata, Rei

× Murata, Rei

WEKO 469026

Murata, Rei

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Takada, Yuki

× Takada, Yuki

WEKO 469027

Takada, Yuki

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Takuwa, Hiroyuki

× Takuwa, Hiroyuki

WEKO 469028

Takuwa, Hiroyuki

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Kawaguchi, Hiroshi

× Kawaguchi, Hiroshi

WEKO 469029

Kawaguchi, Hiroshi

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Ito, Hiroshi

× Ito, Hiroshi

WEKO 469030

Ito, Hiroshi

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Kanno, Iwao

× Kanno, Iwao

WEKO 469031

Kanno, Iwao

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Tottori, Naotomo

× Tottori, Naotomo

WEKO 469032

Tottori, Naotomo

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Yamada, Yukio

× Yamada, Yukio

WEKO 469033

Yamada, Yukio

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Tomita, Yutaka

× Tomita, Yutaka

WEKO 469034

Tomita, Yutaka

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Itoh, Yoshiaki

× Itoh, Yoshiaki

WEKO 469035

Itoh, Yoshiaki

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Suzuki, Norihiro

× Suzuki, Norihiro

WEKO 469036

Suzuki, Norihiro

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Yamada, Katsuya

× Yamada, Katsuya

WEKO 469037

Yamada, Katsuya

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Masamoto, Kazuto

× Masamoto, Kazuto

WEKO 469038

Masamoto, Kazuto

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村田 澪

× 村田 澪

WEKO 469039

en 村田 澪

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高田 優季

× 高田 優季

WEKO 469040

en 高田 優季

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田桑 弘之

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WEKO 469041

en 田桑 弘之

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川口 拓之

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WEKO 469042

en 川口 拓之

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伊藤 浩

× 伊藤 浩

WEKO 469043

en 伊藤 浩

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菅野 巖

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WEKO 469044

en 菅野 巖

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鳥取 直友

× 鳥取 直友

WEKO 469045

en 鳥取 直友

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冨田 裕

× 冨田 裕

WEKO 469046

en 冨田 裕

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正本 和人

× 正本 和人

WEKO 469047

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抄録
内容記述タイプ Abstract
内容記述 The present study examined glucose transfer in the cellular scale of mouse brain microvasculature in vivo using two-photon microscopy and fluorescent glucose analogue (2-NBDG). The 2-NBDG was intravenously injected (0.04 mL/min) in the anesthetized Tie2-GFP mice in which the vascular endothelium expressed fluorescent protein. Time-lapse imaging was conducted on the cortical parenchyma, while the time-intensity change of the injected 2-NBDG was analysed in respective vascular compartments (artery, capillary, and vein). We observed that 2-NBDG signal increased monotonically in the vasculature during the period of the injection, and rapidly declined following its cessation. In tissue compartment, however, the signal intensity gradually increased even after cessation of the injection. Spatiotemporal analysis of the 2-NBDG intensity over the cross-sections of the vessels further showed distinct change of the 2-NBDG intensity across the vessel wall (endothelium), which may represents a regulation site of tissue glucose influx.
書誌情報 Advances in experimental medicine and biology

巻 812, p. 241-246, 発行日 2014-04
出版者
出版者 Kluwer Academic/Plenum Publishers
ISSN
収録物識別子タイプ ISSN
収録物識別子 0065-2598
PubMed番号
識別子タイプ PMID
関連識別子 24729239
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