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Relative biological effectiveness of therapeutic proton beams for HSG cells at Japanese proton therapy facilities
https://repo.qst.go.jp/records/46806
https://repo.qst.go.jp/records/468062f4c7ba1-5454-440c-8127-0ef086bc2778
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-08-20 | |||||
| タイトル | ||||||
| タイトル | Relative biological effectiveness of therapeutic proton beams for HSG cells at Japanese proton therapy facilities | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Aoki, Mizuho
× Aoki, Mizuho× Furusawa, Yoshiya× Uzawa, Akiko× Matsumoto, Yoshitaka× Hirayama, Ryoichi× Tsuruoka, Chizuru× et.al× 青木 瑞穂× 古澤 佳也× 鵜澤 玲子× 松本 孔貴× 平山 亮一× 鶴岡 千鶴 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | We investigated the relative biological effectiveness (RBE) of therapeutic proton beams at six proton facilities in Japan with respect to cell lethality of HSG cells. The RBE of treatments could be determined from experimental data. For this purpose, we used a cell survival assay to compare the cell-killing efficiency of proton beams. Among the five linear accelerator (LINAC) X-ray machines at 4 or 6 MeV that were used as reference beams, there was only a small variation (coefficient of variation CV = 3.1% at D10) in biological effectiveness. The averaged value of D10 for the proton beams at the middle position of the spread-out Bragg peak (SOBP) was 4.98. These values showed good agreement, with a CV of 4.3% among the facilities. Thus, the average RBE10 (RBE at the D10 level) at the middle position of the SOBP beam for six facilities in Japan was 1.05 with a CV of 2.8%. | |||||
| 書誌情報 |
Journal of Radiation Research 巻 55, 号 4, p. 812-815, 発行日 2014-04 |
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| 出版者 | ||||||
| 出版者 | Oxford Univ Press | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0449-3060 | |||||
| PubMed番号 | ||||||
| 識別子タイプ | PMID | |||||
| 関連識別子 | 24699001 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1093/jrr/rru003 | |||||
| 関連サイト | ||||||
| 識別子タイプ | URI | |||||
| 関連識別子 | http://jrr.oxfordjournals.org/content/55/4/812.abstract | |||||
| 関連名称 | http://jrr.oxfordjournals.org/content/55/4/812.abstract | |||||
