@article{oai:repo.qst.go.jp:00046806, author = {Aoki, Mizuho and Furusawa, Yoshiya and Uzawa, Akiko and Matsumoto, Yoshitaka and Hirayama, Ryoichi and Tsuruoka, Chizuru and et.al and 青木 瑞穂 and 古澤 佳也 and 鵜澤 玲子 and 松本 孔貴 and 平山 亮一 and 鶴岡 千鶴}, issue = {4}, journal = {Journal of Radiation Research}, month = {Apr}, note = {We investigated the relative biological effectiveness (RBE) of therapeutic proton beams at six proton facilities in Japan with respect to cell lethality of HSG cells. The RBE of treatments could be determined from experimental data. For this purpose, we used a cell survival assay to compare the cell-killing efficiency of proton beams. Among the five linear accelerator (LINAC) X-ray machines at 4 or 6 MeV that were used as reference beams, there was only a small variation (coefficient of variation CV = 3.1% at D10) in biological effectiveness. The averaged value of D10 for the proton beams at the middle position of the spread-out Bragg peak (SOBP) was 4.98. These values showed good agreement, with a CV of 4.3% among the facilities. Thus, the average RBE10 (RBE at the D10 level) at the middle position of the SOBP beam for six facilities in Japan was 1.05 with a CV of 2.8%.}, pages = {812--815}, title = {Relative biological effectiveness of therapeutic proton beams for HSG cells at Japanese proton therapy facilities}, volume = {55}, year = {2014} }