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Results of carbon ion radiotherapy for head and neck cacer
https://repo.qst.go.jp/records/46764
https://repo.qst.go.jp/records/467642221fd4b-651d-490d-8205-ed8db5f2383a
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-06-27 | |||||
| タイトル | ||||||
| タイトル | Results of carbon ion radiotherapy for head and neck cacer | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Mizoe, Junetsu
× Mizoe, Junetsu× Hasegawa, Azusa× Jingu, Keiichi× Takagi, Ryo× Bessho, Hiroki× Morikawa, Takamichi× Tonogi, Morio× Tsuji, Hiroshi× Kamada, Tadashi× Tsujii, Hirohiko× Okamoto, Yoshitaka× 溝江 純悦× 長谷川 安都佐× 神宮 啓一× 高木 亮× 別所 央城× 森川 貴迪× 外木 守雄× 辻 比呂志× 鎌田 正× 辻井 博彦× 岡本 美孝 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose:To evaluate the efficacy of carbon ion radiotherapy for head-and-neck cancer in a phase II clin-ical trial. Materials and methods:Between April 1997 and February 2006, 236 patients with locally advanced, his-tologically proven, and new or recurrent cancer of the head and neck were treated with carbon ions. The treatment dose was 64.0 GyE/16 fractions/4 weeks(or 57.6 GyE/16 fractions/4 weeks when the wide-range skin was included in the target volume). Results: There were grade 3 acute skin reactions in 6% and grade 3 acute mucosal reactions in 10% with no acute reactions worse than grade 3, and grade 2 late skin reactions in 3% and grade 2 late mucosal reac-tions in 2% with no late reactions worse than grade 2.The 5-year local control rate, by histological type, was 75% for the 85 patients with malignant melanoma, 73% for the 69 with adenoid cystic carcinoma, 73% for the 27 with adenocarcinoma, 61% for the 13 with papillary adenocarcinoma, 61% for the 12 with squa-mous cell carcinoma and 24% for the 14 with sarcomas. The 5-year over-all survival rate was 68% for ade- noid cystic carcinoma, 56% for adenocarcinoma and 35% for malignant melanoma. Conclusions: Carbon ion radiotherapy for head and neck cancer showed the therapeutic effectivaness for malignant melanoma and adenoid cyatic carcinama without severe morbidity of the normal tissues. |
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| 書誌情報 |
Radiotherapy and Oncology 巻 103, 号 1, p. 32-37, 発行日 2012-02 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0167-8140 | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.radonc.2011.12.013 | |||||
