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Preliminary Results from a Multi-center Prospective Study (JROSG 05-5) on Postoperative Radiotherapy for Patients with High-risk Ductal Carcinoma in situ with Involved Margins or Margin Widths 1 mm or less than
https://repo.qst.go.jp/records/46734
https://repo.qst.go.jp/records/46734029f883b-d8de-4206-aa7f-6282018330ae
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2014-03-05 | |||||
| タイトル | ||||||
| タイトル | Preliminary Results from a Multi-center Prospective Study (JROSG 05-5) on Postoperative Radiotherapy for Patients with High-risk Ductal Carcinoma in situ with Involved Margins or Margin Widths 1 mm or less than | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Shikama, Naoto
× Shikama, Naoto× Sekiguchi, Kenji× Nakamura, Naoki× Sekine, Hiroshi× 中山, 優子× Imanaka, Kazufumi× Akiba, Takeshi× Aoki, Masahiko× Hatayama, Yoshiomi× Ogo, Etsuko× Kagami, Yoshikazu× Kawashima, Miho× 唐澤, 久美子× 中山 優子× 唐澤 久美子 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Purpose: This prospective study aimed to evaluate the effectiveness of postoperative radiotherapy (PORT) consisting of whole breast irradiation followed by boost irradiation in patients with high-risk ductal carcinoma in situ (DCIS) with margin widths less than 1mm. Materials and Methods:A multi-center phase II study (Japanese Radiation Oncology Study Group: JROSG 05-5) was conducted to evaluate the effectiveness of PORT. PORT consisted of whole breast irradiation (50Gy/25 fractions) followed by boost irradiation (10Gy/5 fractions) using electron beams for patients with high-risk DCIS. Eligibility criteria were as follows: 1)DCIS without an invasive carcinoma component, 2)age between 20 and 80 years, 3) involved margins or margin widths less than 1 mm, 4) refusal of re-resection, 5) performance status of 0−2, and 6) written informed consent. The primary endpoint was ipsilateral breast tumor recurrence (IBTR), and secondary endpoints were overall survival, relapse free survival, recurrence patterns, and adverse events. |
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| 書誌情報 |
American Journal of Breast Cancer Reserch 巻 1, 号 1, p. 1-8, 発行日 2014-02 |
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| 出版者 | ||||||
| 出版者 | Columbia International Publishing LLC | |||||
