@article{oai:repo.qst.go.jp:00046734,
 author = {Shikama, Naoto and Sekiguchi, Kenji and Nakamura, Naoki and Sekine, Hiroshi and 中山, 優子 and Imanaka, Kazufumi and Akiba, Takeshi and Aoki, Masahiko and Hatayama, Yoshiomi and Ogo, Etsuko and Kagami, Yoshikazu and Kawashima, Miho and 唐澤, 久美子 and 中山 優子 and 唐澤 久美子},
 issue = {1},
 journal = {American Journal of Breast Cancer Reserch},
 month = {Feb},
 note = {Purpose: This prospective study aimed to evaluate the effectiveness of postoperative radiotherapy (PORT) consisting of whole breast irradiation followed by boost irradiation in patients with high-risk ductal carcinoma in situ
(DCIS) with margin widths less than 1mm.
Materials and Methods:A multi-center phase II study (Japanese Radiation Oncology Study Group: JROSG 05-5) was conducted to evaluate the effectiveness of PORT. PORT consisted of whole breast irradiation (50Gy/25 fractions) followed by boost irradiation (10Gy/5 fractions) using electron beams for patients with high-risk DCIS. Eligibility criteria were as follows:
1)DCIS without an invasive carcinoma component, 2)age between 20 and 80 years, 3) involved margins or margin widths less than 1 mm, 4) refusal of re-resection, 5) performance status of 0−2, and 6) written informed consent. The primary endpoint was ipsilateral breast tumor recurrence (IBTR), and secondary endpoints were overall survival, relapse free survival, recurrence patterns, and adverse events.},
 pages = {1--8},
 title = {Preliminary Results from a Multi-center Prospective Study (JROSG 05-5) on Postoperative Radiotherapy for Patients with High-risk Ductal Carcinoma in situ with Involved Margins or Margin Widths 1 mm or less than},
 volume = {1},
 year = {2014}
}