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Prediction of early response to radiotherapy of uterine carcinoma with dynamic contrast-enhanced MR imaging using pixel analysis of MR perfusion imaging
https://repo.qst.go.jp/records/46622
https://repo.qst.go.jp/records/46622be6968e5-eef9-4d40-a8e7-830e8b2dca10
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2013-11-25 | |||||
| タイトル | ||||||
| タイトル | Prediction of early response to radiotherapy of uterine carcinoma with dynamic contrast-enhanced MR imaging using pixel analysis of MR perfusion imaging | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Takayama, Yukihisa
× Takayama, Yukihisa× Ohno, Tatsuya× Kishimoto, Riwa× Kato, Shingo× Yoneyama, Ryuichi× Kandatsu, Susumu× Tsujii, Hirohiko× Obata, Takayuki× 高山 幸久× 大野 達也× 岸本 理和× 加藤 眞吾× 米山 隆一× 神立 進× 辻井 博彦× 小畠 隆行 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | [Purpose] To assess the predictability of the response to radiotherapy of uterine carcinoma, this study retrospectively analyzed dynamic contrast-enhanced magnetic resonance images (DCE-MRI) taken before radiotherapy. [Materials and Methods] Forty-two patients with uterine carcinoma were studied, of whom 22 had adenocarcinoma and 20 had squamous cell carcinoma (SCC). In DCE-MRI analysis, two parameters, SIe and Rdown, were measured. SIe is a median value for the degree of signal intensity change in all selected pixels in the tumor at 1-2 min after contrast agent injection. Rdown is the ratio of the number of down-sloped pixels to that of all selected pixels 3-7 min after injection. The tumor volume reduction rate (TVRR) was measured by MRI-based volumetry in pre- and post-radiotherapy transverse T2-weighted images. [Results] Overall, TVRR was significantly correlated to both SIe (r=0.37, P=.015) and Rdown (r=0.73, P<.0001). In the separate patient groups, SIe but not Rdown was significantly different between the adenocarcinoma and SCC patients (t=3.64, P<.001). TVRR was not correlated to SIe in any group. TVRR was significantly correlated to Rdown in adenocarcinoma patients (r=0.78, P<.001) but not in SCC patients. [Conclusion] SIe may reflect differences in histological characteristics. Rdown may be useful for predicting the response to radiotherapy of uterine carcinoma. |
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| 書誌情報 |
Magnetic Resonance Imaging 巻 27, 号 3, p. 370-376, 発行日 2008-09 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0730-725X | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1016/j.mri.2008.07.007 | |||||
