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Biochemical failure after carbon ion radiotherapy for prostate cancer
https://repo.qst.go.jp/records/46377
https://repo.qst.go.jp/records/463779dbb343c-230e-4d41-afa8-01ea7ed1beda
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2012-08-09 | |||||
| タイトル | ||||||
| タイトル | Biochemical failure after carbon ion radiotherapy for prostate cancer | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| アクセス権 | ||||||
| アクセス権 | metadata only access | |||||
| アクセス権URI | http://purl.org/coar/access_right/c_14cb | |||||
| 著者 |
Shimazaki, Jun
× Shimazaki, Jun× Tsuji, Hiroshi× Ishikawa, Hitoshi× Kamada, Tadashi× Harada, Masaoki× Akakura, Kouichirou× Suzuki, Hiroyosi× Tomohiko, Ichikawa× Tsujii, Hirohiko× 島崎 淳× 辻 比呂志× 石川 仁× 鎌田 正× 原田 昌興× 赤倉 功一郎× 鈴木 啓悦× 市川 智彦× 辻井 博彦 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Abstract Background/Aim: Biochemical failure after radiotherapy for prostate cancer occurs infrequently, but some cases progress to a poor outcome. The aim of this study was to examine prognosis after biochemical failure. \nPATIENTS AND METHODS: A total of 728 patients were treated with carbon ion radiotherapy, and biochemical failure occurred in 90 (12.4%). Their outcomes were examined according to risk factors, histological findings, and androgen deprivation therapy (ADT). \nRESULTS: Biochemical failure rates were 12%, 6%, and 15% in low-, intermediate- and high-risk patients. Most patients responded favorably to salvage therapy. Some high-risk patients (25%) progressed to poor outcome; half experienced failure after ADT, while the rest during ADT, indicating that ADT had a slight influence. Patients who died from their disease had approximately two years of biochemical failure-free time and three years of survival after failure. Their tumor showed the presence and the increased proportion of histologically high-grade growth patterns. \nCONCLUSION: Histological growth patterns and short biochemical failure-free time are prognostic factors for poor outcome regardless of ADT. |
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| 書誌情報 |
Anticancer Research 巻 32, 号 8, p. 3267-3273, 発行日 2012-08 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0250-7005 | |||||
